Family 01 · CAS 9067-32-7

Sodium hyaluronate

Non-animal, bacterial-fermentation hyaluronate in six documented grades, each available across the full 15–1645 kDa molecular-weight window. The grade sets purity, endotoxin and documentation; you choose the molecular weight.

Sodium hyaluronate powder — 4MedChem

15–1645 kDa
molecular weight range
≥ 95%
assay, dry basis
Non-animal
streptococcal fermentation
2–3 weeks
lead time · 10 g to 25 kg

Grade specifications

MW by SEC-MALS · endotoxin by LAL

GradeMW (kDa), you specifyAssayEndotoxinProteinTypical useDetails
Eye grade15–1645≥ 95%≤ 0.05 EU/mg≤ 0.05%Ophthalmic viscosurgery, IOL implantationDetails →
Sterile15–1645≥ 95%≤ 0.05 EU/mg≤ 0.05%Intra-articular injection, sterile gelsDetails →
Pharma / EP grade15–1645≥ 95%≤ 0.5 EU/mg≤ 0.1%Dermal filler, topical formulationDetails →
Cosmetic15–1645≥ 95%≤ 0.5 EU/mg≤ 0.1%Serums, creams, hydrationDetails →
Medical device15–1645≥ 95%≤ 0.5 EU/mg≤ 0.1%Wound care, device coatingsDetails →
Low MW / oligo≤ 15≥ 95%≤ 0.5 EU/mg≤ 0.1%Skin penetration, oral, researchDetails →

Assay is ≥ 95% on every grade. Every grade except the low-MW / oligo material is available across the full 15–1645 kDa window — you specify the molecular weight, we set the fermentation and downstream processing accordingly. Lot-specific results are stated on the certificate of analysis.

Choosing a molecular weight

> 1200 kDa
Maximum viscoelasticity
Space maintenance in the anterior chamber and long joint residence time. Shear-thinning, harder to filter.
400–1200 kDa
Balanced workhorse
Injectable viscosity with manageable processing. The usual starting point for crosslinked filler gels.
< 400 kDa
Penetration and coating
Low solution viscosity at high solids — thin lubricious coatings, sprays and topical uptake.

Applications

Ophthalmic viscosurgery
High-MW eye grades for OVD and intraocular lens implantation.
Intra-articular injection
Sterile grades for viscosupplementation of synovial fluid.
Dermal fillers & topicals
Pharma and cosmetic grades for crosslinked gels and formulation.
Wound care & coatings
Low-MW device grades for lubricious and hydrophilic coatings.

Handling & documentation

AppearanceWhite to off-white powder
OriginStreptococcus fermentation, non-animal
Loss on drying≤ 10%
Heavy metals≤ 20 ppm
Storage2–8 °C, sealed, dry
Packaging10 g, 100 g, 1 kg, 25 kg
DocumentationCoA, spec sheet, TSE/BSE statement

Specification sheets and regulatory documentation available on request, under NDA where needed.

Not sure which MW you need?

Tell us the viscosity target and sterilisation route — we suggest a grade, send a sample for qualification and quote your production volume.

✓ Samples for qualification
✓ CoA and specification sheets
✓ NDA on request
Technical sales · hyaluronate
+31 6 2189 0936
info@4medchem.com

Request information to a specialist

Other families in this category

Family 02
PLGA polymers
+15 grades

 


Family 03
Hydrogels from oxazolines
+10 grades

 

Request information

Tell us the grade, molecular weight and quantity you are looking at. A specialist replies with documentation and a price, usually the same working day.

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